Germain L, Lamarre Y
Département de physiologie, Université de Montréal, Qué., Canada.
Brain Res. 1993 May 14;611(1):175-9. doi: 10.1016/0006-8993(93)91792-q.
In order to assess the effect of learning a conditional motor task on set-related cells of the precentral cortex we recorded a total of 228 task-related cells in awake, behaving primate. A first sample of 54 set-related cells was recorded while the monkey was performing at 54.7 +/- 7.8% and a second sample of 119 set-related cells was recorded at the same stereotaxic coordinates while he was performing at 77.2 +/- 8.7%. After the monkey had learned the association between an auditory signal and a motor response we found a significant increase in the proportion and activity of directional set-related cells in the premotor cortex. Furthermore the proportion of short-latency set-related cells was found to increase in this area. None of those changes were observed in the motor cortex.
为了评估学习条件性运动任务对中央前回与定势相关细胞的影响，我们在清醒、行为活动的灵长类动物中总共记录了228个与任务相关的细胞。在猴子以54.7±7.8%的正确率执行任务时，记录了54个与定势相关细胞的第一个样本；在相同立体定位坐标下，当猴子以77.2±8.7%的正确率执行任务时，记录了119个与定势相关细胞的第二个样本。在猴子学会听觉信号与运动反应之间的关联后，我们发现运动前皮质中定向定势相关细胞的比例和活动显著增加。此外，该区域中短潜伏期定势相关细胞的比例也有所增加。而在运动皮质中未观察到这些变化。
