Gorshein D
Cancer. 1977 Apr;39(4):1700-3. doi: 10.1002/1097-0142(197704)39:4<1700::aid-cncr2820390446>3.0.co;2-a.
Abnormalities in taste sensation have been studied in 15 patients consisting of five normal controls, five patients with diffuse neoplasm and five patients post hypophysectomy. Threshold recognition for salt and HC1 in the three groups studied was the same. Sucrose and urea recognition was higher in patients with neoplasm as compared to normal controls. Patients post hypophysectomy had a lower threshold recognition for sucrose than both normal individuals and patients with neoplasm. The threshold recognition has markedly shifted for both sucrose (decreased) and urea (increased) post hypophysectomy. These observations are in support of previous findings and suggest that the pituitary plays at least a necessary permissible factor in the development of abnormalities in taste as observed in patients with disseminated cancer.
对15名患者的味觉异常进行了研究，其中包括5名正常对照者、5名弥漫性肿瘤患者和5名垂体切除术后患者。所研究的三组患者对盐和盐酸的阈值识别相同。与正常对照者相比，肿瘤患者对蔗糖和尿素的识别率更高。垂体切除术后患者对蔗糖的阈值识别低于正常人和肿瘤患者。垂体切除术后，蔗糖（降低）和尿素（升高）的阈值识别均有明显变化。这些观察结果支持了先前的发现，并表明垂体在播散性癌症患者中观察到的味觉异常发展中至少起着必要的允许因素的作用。
