Sagliocca L, Mele A, Ferrigno L, Palumbo F, Converti F, Tosti M E, Amoroso P, Manzillo G
Regione Campania, Osservatorio Epidemiologico, Napoli, Italy.
Ital J Gastroenterol. 1995 May;27(4):181-4.
An increased incidence of hepatitis A was observed in Naples from 1990-1991. A hospital-based case-control study was carried out to evaluate the relative importance of various risk factors. A hundred and ninety-eight cases and 238 hospital controls were recruited during the study period. The strongest association was contact with a jaundiced person among children. A correlation was also shown for children and adults with raw shellfish consumption and pre-school nursery attendance or presence in the household of children attending pre-school nurseries. History of travel and intravenous drug use were risk factors for adult subjects. Considering the relative importance of the specific risk factors we found that 38% of the acute hepatitis A cases were attributable to contact with a jaundiced person, 15% to presence in the household of children attending pre-school nurseries and 28% to raw shellfish consumption.
1990年至1991年期间，那不勒斯甲型肝炎发病率上升。开展了一项基于医院的病例对照研究，以评估各种风险因素的相对重要性。研究期间招募了198例病例和238名医院对照。儿童中与黄疸患者接触的关联最为强烈。对于食用生贝类以及儿童在幼儿园上学或家中有上幼儿园儿童的儿童和成人，也显示出相关性。旅行史和静脉注射吸毒是成年受试者的风险因素。考虑到特定风险因素的相对重要性，我们发现38%的急性甲型肝炎病例可归因于与黄疸患者接触，15%可归因于家中有上幼儿园儿童，28%可归因于食用生贝类。
