BELL1基因编码一种参与拟南芥胚珠原基模式形成的同源结构域蛋白。
The BELL1 gene encodes a homeodomain protein involved in pattern formation in the Arabidopsis ovule primordium.
作者信息
Reiser L, Modrusan Z, Margossian L, Samach A, Ohad N, Haughn G W, Fischer R L
机构信息
Department of Plant Biology, University of California, Berkeley 94720, USA.
出版信息
Cell. 1995 Dec 1;83(5):735-42. doi: 10.1016/0092-8674(95)90186-8.
Ovule development in Arabidopsis involves the formation of three morphologically defined proximal-distal pattern elements. Integuments arise from the central pattern element. Analysis of Bell 1 (Bel 1) mutant ovules indicated that BEL1 was required for integument development. Cloning of the BEL1 locus reveals that it encodes a homeodomain transcription factor. Prior to integument initiation, BEL1 RNA localizes to the central domain, providing molecular evidence for a central pattern element. Therefore, proximal-distal patterning of the ovule involves the regulated expression of the BEL1 gene that controls integument morphogenesis. A model for BEL1 function is evaluated with regard to new data showing the expression pattern of the floral homeotic gene AGAMOUS (AG) early in wild-type and BEL1 ovule development.
拟南芥胚珠的发育涉及形成三个形态学上定义的近远轴模式元件。珠被起源于中央模式元件。对Bell 1（Bel 1）突变体胚珠的分析表明，BEL1是珠被发育所必需的。BEL1基因座的克隆显示它编码一个同源异型结构域转录因子。在珠被起始之前，BEL1 RNA定位于中央结构域，为中央模式元件提供了分子证据。因此，胚珠的近远轴模式形成涉及控制珠被形态发生的BEL1基因的调控表达。根据显示野生型和BEL1胚珠发育早期花同源异型基因AGAMOUS（AG）表达模式的新数据，对BEL1功能模型进行了评估。
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