大鼠丙酮酸羧化酶编码cDNA的序列。

The sequence of the rat pyruvate carboxylase-encoding cDNA.

作者信息

Lehn D A, Moran S M, MacDonald M J

机构信息

Childrens Diabetes Center, University of Wisconsin, Madison 53706, USA.

出版信息

Gene. 1995 Nov 20;165(2):331-2. doi: 10.1016/0378-1119(95)00557-m.

DOI:10.1016/0378-1119(95)00557-m

PMID:8522203

Abstract

A composite 3945-bp cDNA that encodes rat pyruvate carboxylase (PC) has been constructed from clones isolated from a rat liver cell cDNA library and the nucleotide sequence has been determined. The rat cDNAs open reading frame encodes a protein of 1178 amino acids that is 98.6% identical (99.0% similar) to that of mouse PC and 96.0% identical (97.8% similar) to that of human PC.

摘要

一个编码大鼠丙酮酸羧化酶（PC）的3945碱基对复合cDNA已从大鼠肝细胞cDNA文库中分离的克隆构建而成，其核苷酸序列也已确定。大鼠cDNA的开放阅读框编码一个1178个氨基酸的蛋白质，该蛋白质与小鼠PC的同源性为98.6%（相似性为99.0%），与人类PC的同源性为96.0%（相似性为97.8%）。