Griffiths D, Wass J, Look K, Sutton G
Department of Obstetrics and Gynecology, Indiana University Medical Center, Indianapolis 46202, USA.
Gynecol Oncol. 1995 Dec;59(3):427-9. doi: 10.1006/gyno.1995.9948.
Malignant degeneration of mature cystic teratomas has been reported in 1-3% of cases. A patient with the unusual occurrence of a stage IIIC squamous cell carcinoma arising in a mature teratoma over 50 years after initial diagnosis is presented. The patient was treated with pelvic radiotherapy. The role of serum squamous cell carcinoma antigen in detecting degeneration of mature cystic teratomas at an early stage is considered.
据报道，成熟囊性畸胎瘤的恶性变发生率为1%-3%。本文介绍了一例患者，其在初次诊断50多年后，成熟畸胎瘤中出现了罕见的IIIC期鳞状细胞癌。该患者接受了盆腔放疗。文中还探讨了血清鳞状细胞癌抗原在早期检测成熟囊性畸胎瘤恶变中的作用。
