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婴儿和新生儿主动脉缩窄:结果及预后变量评估

Coarctation of the aorta in infants and neonates: results and assessment of prognostic variables.

作者信息

Demircin M, Arsan S, Pasaoglu I, Atasoy S, Sarigül A, Dogan R, Ispir S, Yurdakul Y, Bozer A Y

机构信息

Department of Thoracic and Cardiovascular Surgery, Hacettepe University Hospital, Ankara, Turkey.

出版信息

J Cardiovasc Surg (Torino). 1995 Oct;36(5):459-64.

PMID:8522563
Abstract

From 1984 until 1994, 75 consecutive patients younger than 12 months of age were operated on for coarctation of the aorta. We retrospectively analyzed predictive factors for morbidity and mortality, and also interaction between surgical procedures and recoarctation. Surgical procedures were as follows: resection with a traditional end-to-end (E-E) anastomosis in 55 patients (73.3%), prosthetic patch aortoplasty (PPA) in 12 patients (16%) and subclavian flap aortoplasty (SFA) in 8 patients (10.7%). Early mortality was 9.33% (7 patients). Logistic regression analysis proved that age at operation, associated anomalies of heart, type of coarctation, aortic arch hypoplasia and pulmonary banding were independent predictors of hospital death. Late mortality occurred in 7 patients (10.3%). Associated anomalies of heart were an independent prognostic factor for late mortality. Actuarial freedom from recoarctation at 1 year was 91% [confidence limits (CL): 82% to 97%] and 5 years were 74% (CL: 67% to 86%). Immediate postrepair gradient was equal after E-E anastomosis and other procedures. We conclude that the treatment of first choice in the management of coarctation of the aorta in infants is E-E anastomosis.

摘要

1984年至1994年期间,75例年龄小于12个月的连续患者接受了主动脉缩窄手术。我们回顾性分析了发病率和死亡率的预测因素,以及手术方式与再缩窄之间的相互作用。手术方式如下:55例患者(73.3%)采用传统端端(E-E)吻合术进行切除,12例患者(16%)采用人工补片主动脉成形术(PPA),8例患者(10.7%)采用锁骨下动脉瓣主动脉成形术(SFA)。早期死亡率为9.33%(7例患者)。逻辑回归分析证明,手术年龄、心脏相关畸形、缩窄类型、主动脉弓发育不全和肺动脉环扎是医院死亡的独立预测因素。7例患者(10.3%)发生晚期死亡。心脏相关畸形是晚期死亡的独立预后因素。1年时无再缩窄的精算自由度为91%[置信区间(CL):82%至97%],5年时为74%(CL:67%至86%)。E-E吻合术和其他手术术后即刻压差相等。我们得出结论,婴儿主动脉缩窄治疗的首选方法是E-E吻合术。

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