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初次全髋关节置换术中血液回收技术的前瞻性随机评估

Prospective randomized evaluation of blood salvage techniques for primary total hip arthroplasty.

作者信息

Rollo V J, Hozack W J, Rothman R H, Chao W, Eng K O

机构信息

Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

J Arthroplasty. 1995 Aug;10(4):532-9. doi: 10.1016/s0883-5403(05)80157-3.

Abstract

A controlled, randomized, prospective study was performed evaluating the need for perioperative blood salvage for primary total hip arthroplasty patients who had donated autologous blood before surgery. One hundred fifty-three patients able to donate at least 2 units of autologous blood were divided into four groups. In group 1 (35 patients), intraoperative and postoperative Cell-Saver (Haemonetics, Braintree, MA) was employed. In group 2 (40 patients), a postoperative Solcotrans (Smith & Nephew Richards, Memphis, TN) reinfusion protocol was followed. In group 3 (40 patients), a closed-suction Hemovac drain (Zimmer, Warsaw, IN) was placed. In group 4, (38 patients), no drain was used. Decisions for transfusion were based on clinical and laboratory parameters and made in conjunction with medical consultation. All autologous blood was routinely reinfused. There was no statistically significant difference in transfusion requirements or wound complications among the four groups. Hemoglobin and hematocrit changes between groups also were not statistically significant, but a power test suggested insufficient patient numbers for absolute reliability of this observation. Only five patients (3.3%) in this study received homologous blood. Four of these patients were in the Solcotrans group and one was in the Cell-Saver group. Two reoperations were performed: one for hematoma (Solcotrans group) and one for a sewn-in drain. It is concluded that expensive perioperative blood salvage techniques are usually not needed in patients who have a primary total hip arthroplasty without cement and who have donated 2 units of blood before operation.

摘要

对术前已捐献自体血的初次全髋关节置换术患者进行了一项对照、随机、前瞻性研究,以评估围手术期血液回收的必要性。153名能够捐献至少2单位自体血的患者被分为四组。第1组(35例患者)术中及术后使用血液回收机(Haemonetics公司,马萨诸塞州布伦特里)。第2组(40例患者)采用术后Solcotrans(史赛克理查兹公司,田纳西州孟菲斯)回输方案。第3组(40例患者)放置封闭式负压引流Hemovac引流管(捷迈公司,印第安纳州华沙)。第4组(38例患者)不使用引流管。输血决策基于临床和实验室参数,并在医学咨询的基础上做出。所有自体血均常规回输。四组之间在输血需求或伤口并发症方面无统计学显著差异。组间血红蛋白和血细胞比容变化也无统计学显著差异,但效能检验表明患者数量不足以使该观察结果具有绝对可靠性。本研究中只有5名患者(3.3%)接受了异体血。其中4名患者在Solcotrans组,1名患者在血液回收机组。进行了两次再次手术:一次是因血肿(Solcotrans组),一次是因内置引流管。得出的结论是,对于初次非骨水泥型全髋关节置换术且术前已捐献2单位血液的患者,通常不需要昂贵的围手术期血液回收技术。

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