McCarty D J, Harman J G, Grassanovich J L, Qian C
Department of Medicine, Medical College of Wisconsin, Milwaukee 53226, USA.
J Rheumatol. 1995 Sep;22(9):1631-5.
To determine the effectiveness of intrasynovial triamcinolone hexacetonide coupled with joint rest (3 weeks upper extremity; 6 weeks lower extremity) in the treatment of joint and tendon sheath inflammation in patients with seropositive rheumatoid arthritis (RA).
The medical records of 169 patients with seropositive RA treated by a single rheumatologist for at least one year between 1974 and 1992 were abstracted.
Nine hundred fifty-six injections were given to 140 patients; approximately 75% of injected synovial structures remained in remission during a mean followup 7 years; 218 injections were given into previously treated structures. The injection rate was about 2 per patient in the first year, half of which were given at the time of the first visit. The rate then approximated 0.6 injections per patient-year for the next 15 years. Joints in the right upper extremity were injected significantly (p = 0.01) more frequently than those on the left.
Intrasynovial triamcinolone hexacetonide followed by rest is a very useful adjunctive modality in the treatment of seropositive rheumatoid arthritis.
确定关节内注射己曲安奈德并结合关节制动（上肢3周；下肢6周）治疗血清反应阳性类风湿关节炎（RA）患者关节和腱鞘炎症的有效性。
提取了1974年至1992年间由一名风湿病专家治疗至少一年的169例血清反应阳性RA患者的病历。
对140例患者进行了956次注射；在平均7年的随访期间，约75%的注射滑膜结构保持缓解状态；对先前治疗过的结构进行了218次注射。第一年每位患者的注射率约为2次，其中一半在首次就诊时进行。在接下来的15年中，每位患者每年的注射率约为0.6次。右上肢关节的注射频率明显高于左上肢关节（p = 0.01）。
关节内注射己曲安奈德后制动是治疗血清反应阳性类风湿关节炎非常有用的辅助方法。
