Clive J M, Spencer R P
University of Connecticut Health Center, Farmington 06030-2804, USA.
Mech Ageing Dev. 1995 Aug 31;83(1):31-41. doi: 10.1016/0047-6374(95)01608-3.
Age-specific mortality from carcinoma of the prostate was analyzed by drawing a line between the value at age 52 years and that at age 87. Slope of the line was relatively constant for the pooled years 1962-1966, 1967-1971 and 1972-1976 (maximum variation from the mean of 4.5%). However, the slope was 17.7% greater for the period 1977-1981 and 29.8% over the prior mean in 1987-1992. This was explored by two models. Mortality versus age was well described by a power function, with an increase in slope noted in the mid-1970s. An exponential growth model was also utilized and revealed the existence of a 'change point' around the year 1975. Hence, two models are available for further exploring the increase in age-specific mortality from carcinoma of the prostate which occurred in the mid-1970 period.
通过在52岁和87岁时的值之间画一条线,分析了前列腺癌的年龄特异性死亡率。对于1962 - 1966年、1967 - 1971年和1972 - 1976年这几个合并年份,该线的斜率相对恒定(与均值的最大变化为4.5%)。然而,1977 - 1981年期间的斜率比之前大17.7%,1987 - 1992年比之前的均值大29.8%。这通过两个模型进行了探究。死亡率与年龄的关系可用幂函数很好地描述,在20世纪70年代中期斜率有所增加。还使用了指数增长模型,该模型揭示在1975年左右存在一个“变化点”。因此,有两个模型可用于进一步探究20世纪70年代中期发生的前列腺癌年龄特异性死亡率的增加情况。