Millen S J, Haughton V M, Yetkin Z
Rhinological and Otological Society, Inc, Omaha.
Laryngoscope. 1995 Dec;105(12 Pt 1):1305-10. doi: 10.1288/00005537-199512000-00008.
Functional magnetic resonance imaging (FMRI) is a new noninvasive technique for imaging cerebral function. Studies of the human central auditory pathway examined responses in eight normal hearing volunteers following auditory stimuli, including narrative speech and pure-tone audiometry. The activation demonstrated by FMRI is modeled on an increase in regional blood flow with increased neuronal activity. The FMRI signals represent deoxyhemoglobin concentration changes in capillaries within the region of the brain that is activated. Brain activation was imaged in the superior temporal gyrus during text reading and pure tones. Activation in both text and pure-tone presentation did not vary with the intensity of the auditory stimulus and elicited a dominant response in the left temporal lobe. These observations demonstrate the capability of FMRI to correlate anatomic and functional relationships in the human central auditory pathway.
功能磁共振成像（FMRI）是一种用于脑功能成像的新型非侵入性技术。对人类中枢听觉通路的研究检测了八名听力正常的志愿者在接受包括叙述性言语和纯音听力测定在内的听觉刺激后的反应。FMRI显示的激活是基于神经元活动增加时局部血流增加的模型。FMRI信号代表被激活的脑区毛细血管内脱氧血红蛋白浓度的变化。在文本阅读和纯音刺激过程中，颞上回的脑激活情况被成像。文本和纯音呈现时的激活情况均不随听觉刺激强度而变化，且在左颞叶引发了主要反应。这些观察结果证明了FMRI能够关联人类中枢听觉通路中的解剖学和功能关系。
