Erhard W, Reichmann M, Delius W, Sebening H, Herrmann G
Dtsch Med Wochenschr. 1977 Apr 22;102(16):615-9. doi: 10.1055/s-0028-1104942.
210 patients were followed up by the actuary method for over 5 years after isolated mitral valve replacement or a double valve replacement. After isolated valve replacement the one month survival including the operative mortality was 92+/-2%. The survival after one year was 83+/-3% and after 5 years 66+/-7%. The five year survival of patients in preoperative class III (according to the NYHA) was 73+/-8% and of class IV 57+/-8% (P less than or equal to 0.1). A comparison of valve replacements for pure mitral stenosis or mitral insufficiency showed no statistically significant differences. In the 37 patients who had a double valve replacement the survival risk was not increased in comparison with those patients who had had a single valve replacement. Age above 45 years and a preoperative markedly raised pulmonary arteriolar resistance reduced the chances of survival.
对210例患者在单纯二尖瓣置换术或双瓣置换术后采用精算方法进行了5年以上的随访。单纯瓣膜置换术后，包括手术死亡率在内的1个月生存率为92±2%。1年后生存率为83±3%，5年后为66±7%。术前心功能Ⅲ级（根据纽约心脏协会分级）患者的5年生存率为73±8%，Ⅳ级患者为57±8%（P≤0.1）。单纯二尖瓣狭窄或二尖瓣关闭不全的瓣膜置换术比较，无统计学显著差异。在37例接受双瓣置换术的患者中，与接受单瓣置换术的患者相比，生存风险并未增加。45岁以上以及术前肺小动脉阻力明显升高会降低生存几率。
