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[外源性物质诱导的实验性结核病联合治疗中组织反应的形态学特征]

[Morphological features of tissue reactions in combined treatment of experimental tuberculosis induced by xenobiotics].

作者信息

Pavlov V A, Kazak T I, Kleĭn A V, Nosova N A

出版信息

Probl Tuberk. 1995(6):32-5.

PMID:8524767
Abstract

The trend to aggravated running and contribution of air pollution of large industrial centers with polycyclic aromatic hydrocarbons (PAH) to tuberculosis onset and progress dictate the necessity of the search for new treatment methods. The authors made an attempt to treat experimental tuberculosis with sodium glutamate and isoniazide under chronic exposure to PAH dust. Sodium glutamate especially in combination with isoniazide produces a good effect enhancing granulomatous reactions fibroplastic processes in the foci of specific inflammation. Sodium glutamate is thought an effective pathogenetic treatment of tuberculosis.

摘要

剧烈运动的趋势以及大型工业中心含多环芳烃(PAH)的空气污染对结核病发病和进展的影响,决定了寻找新治疗方法的必要性。作者尝试在长期暴露于PAH粉尘的情况下,用谷氨酸钠和异烟肼治疗实验性结核病。谷氨酸钠尤其是与异烟肼联合使用时,能产生良好效果,增强特异性炎症病灶中的肉芽肿反应和成纤维过程。谷氨酸钠被认为是结核病有效的病因治疗药物。

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