测量慢性肾脏病患者的肾功能。
Measurement of renal function in patients with chronic kidney disease.
机构信息
National Poisons Information Service Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.
出版信息
Br J Clin Pharmacol. 2013 Oct;76(4):504-15. doi: 10.1111/bcp.12198.
Abstract
Chronic kidney disease affects millions of people worldwide and is associated with an increased morbidity and mortality as a result of kidney failure and cardiovascular disease. Accurate assessment of kidney function is important in the clinical setting as a screening tool and for monitoring disease progression and guiding prognosis. In clinical research, the development of new methods to measure kidney function accurately is important in the search for new therapeutic targets and the discovery of novel biomarkers to aid early identification of kidney injury. This review considers different methods for measuring kidney function and their contribution to the improvement of detection, monitoring and treatment of chronic kidney disease.
摘要
慢性肾脏病影响着全球数以百万计的人群，并且由于肾衰竭和心血管疾病的发生，其发病率和死亡率也有所增加。在临床环境中，准确评估肾功能非常重要，它既是一种筛查工具，也可以用于监测疾病进展并指导预后。在临床研究中，开发新的方法来准确测量肾功能对于寻找新的治疗靶点和发现新的生物标志物以帮助早期识别肾损伤非常重要。本文综述了不同的肾功能测量方法及其对提高慢性肾脏病的检测、监测和治疗水平的贡献。
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