Hoyos A, Gutiérrez J, Piédrola G
Departamento de Microbiología, Hospital Universitario San Cecilio, Universidad de Granada, España.
Rev Med Chil. 1995 Apr;123(4):473-8.
Enterococci resistance to antimicrobials has increased lately. We studied the susceptibility to 12 antimicrobials of 150 enterococci strains coming from hospitalized and outpatients, using the agar dilution method. Teicoplanin, followed by imipenem and amoxicilin-clavulanic acid had the lower minimal inhibitory concentrations. No strains of E faecalis was resistant to ampicillin, whereas 14% of E faecium had minimal inhibitory concentrations over 8 micrograms/ml. The high minimal inhibitory concentrations of cefpirome (64 micrograms/ml) renders this antimicrobial useless in the treatment of enterococcal infections. Betalactamase production and resistance to glucopeptides were not detected. Antimicrobial susceptibility of strains coming for hospitalized or outpatients were similar.
近年来，肠球菌对抗菌药物的耐药性有所增加。我们采用琼脂稀释法，研究了150株来自住院患者和门诊患者的肠球菌对12种抗菌药物的敏感性。替考拉宁，其次是亚胺培南和阿莫西林 - 克拉维酸的最低抑菌浓度较低。粪肠球菌菌株对氨苄西林均无耐药性，而屎肠球菌中有14%的最低抑菌浓度超过8微克/毫升。头孢匹罗的高最低抑菌浓度（64微克/毫升）使其在治疗肠球菌感染中毫无用处。未检测到β-内酰胺酶的产生和对糖肽类的耐药性。来自住院患者或门诊患者的菌株的抗菌药物敏感性相似。
