Vikhliaev Iu I, Zherdev V P, Gritsenko A N, Ermakova Z I
Farmakol Toksikol. 1977 Jan-Feb;40(1):19-22.
A study of the aethozine metabolism in the urine of rats detected 14 metabolites, a number of which was identified, namely: 2-aminophenothiazine, 2-acetylamide-phenothiazine, ethyl ether of phenothiazine-carbamine-2-acid, their sulphoxides and also aethmozine sulphoxide. Of the aethmozine biotransformation processes is characteristic formation in the organism of the animals of significant quantities of transformation products with complete degradation of the side chain.
一项对大鼠尿液中乙噻嗪代谢情况的研究检测到14种代谢物，其中一些已被鉴定出来，即：2-氨基吩噻嗪、2-乙酰酰胺基吩噻嗪、吩噻嗪-脲-2-酸乙酯醚、它们的亚砜以及乙噻嗪亚砜。在动物机体中，乙噻嗪的生物转化过程的特征是形成大量带有侧链完全降解的转化产物。
