Bresler L, Courbey P J, Feldman L, Bilweiss J, Tortuyaux J M, Rauch P, Boissel P, Grosdidier J
Clinique Chirurgicale C, CHRU de Nancy, Hôpitaux de Brabois, Vandoeuvre-les-Nancy.
Ann Chir. 1995;49(6):544-8.
A randomized prospective trial was carried out between September 1987 and February 1989 to compare 3 different absorbable sutures (polyglactine 910, polydioxanone I, polydioxanone II) for closure of the abdominal wall after upper midline laparotomy for elective operations. The technique used to close the fascia was always a continuous suture. The criteria used to assess the results were the development of wound infection and wound dehiscence in the early postoperative period, and the development of suture sinuses and incisional hernia 1 year after operation. The early postoperative results in 235 patients revealed no wound infection and no -wound dehiscence. Suture sinuses developed in 4 patients (2%) 2 months after operation, but resolved spontaneously. We reviewed 203 patients after one year. The total number of incisional hernias detected 1 year postoperatively was 22 cases (11%), (polyglactine 910, 14.2%; polydioxanone I, 11.2%; polydioxanone II, 8.4%). The difference between the 3 groups was not statistically significant. The results of the trial indicate that absorbable sutures have a very low incidence of suture sinuses, and that polydioxanone II seems to be a good choice for closing laparotomies.
1987年9月至1989年2月期间进行了一项随机前瞻性试验，比较3种不同的可吸收缝线（聚乙醇酸910、聚二氧杂环己酮I、聚二氧杂环己酮II）用于择期手术中上腹部正中剖腹术后腹壁闭合的效果。关闭筋膜所采用的技术始终为连续缝合。用于评估结果的标准为术后早期伤口感染和伤口裂开的发生情况，以及术后1年缝线窦道和切口疝的发生情况。235例患者的术后早期结果显示无伤口感染和伤口裂开。4例患者（2%）术后2个月出现缝线窦道，但自行消退。1年后我们对203例患者进行了复查。术后1年检测到的切口疝总数为22例（11%），（聚乙醇酸910为14.2%；聚二氧杂环己酮I为11.2%；聚二氧杂环己酮II为8.4%）。3组之间的差异无统计学意义。试验结果表明，可吸收缝线的缝线窦道发生率非常低，聚二氧杂环己酮II似乎是用于剖腹手术闭合的一个不错选择。
