Waters J C, Salmon E D
University of North Carolina, Biology Dept. Chapel Hill 27599-328, USA.
Bioessays. 1995 Nov;17(11):911-4. doi: 10.1002/bies.950171102.
The assembly of a bipolar spindle is essential for the accurate segregation of replicated chromosomes during cell division. Do chromosomes rely solely on other cellular components to regulate the assembly of the bipolar spindle or are they masters of their own fate? In the Zhang and Nicklas(1) study reviewed here, micromanipulation techniques and video microscopy were used to demonstrate the different roles that chromosome arms, kinetochores and centrosomes play in bipolar spindle assembly.
双极纺锤体的组装对于细胞分裂过程中复制染色体的精确分离至关重要。染色体是仅仅依赖其他细胞成分来调控双极纺锤体的组装，还是它们自身命运的主宰者呢？在本文所综述的张和尼克拉斯的研究中，运用了显微操作技术和视频显微镜来证明染色体臂、动粒和中心体在双极纺锤体组装中所起的不同作用。
