Jerosch J, Fuchs S, Liljenqvist U, Haftka A
Westfälische Wilhelms-Universität Münster.
Biomed Tech (Berl). 1995 Oct;40(10):296-303.
We investigated the influence of different sterilization techniques on the degree of oxidation of UHMWPE. Oxidation effects were documented by infrared spectroscopy. The UHMWPE was sterilized with the aid of gamma radiation (2.5 Mrad) in air, gamma radiation in argon, ethylene oxide and autoclaving. Non-sterilized UHMWPE served as control material. The results showed significant differences for the various sterilization techniques employed. The highest degree of oxidation was seen after autoclaving, but gamma radiation was also associated with a significant degree of oxidation. Using gamma radiation in argon, the degree of oxidation was significantly reduced. Following sterilization with ethylene oxide, no oxidation was to be found. In view of these facts, UHMWPE should be sterilized only with ethylene oxide or with gamma radiation in argon.
我们研究了不同灭菌技术对超高分子量聚乙烯（UHMWPE）氧化程度的影响。通过红外光谱记录氧化效应。UHMWPE分别在空气中借助γ射线（2.5兆拉德）、在氩气中进行γ射线照射、使用环氧乙烷以及高压灭菌进行灭菌处理。未灭菌的UHMWPE作为对照材料。结果显示，所采用的各种灭菌技术存在显著差异。高压灭菌后氧化程度最高，但γ射线照射也会导致显著的氧化程度。在氩气中使用γ射线照射时，氧化程度显著降低。用环氧乙烷灭菌后，未发现氧化现象。鉴于这些事实，UHMWPE应仅采用环氧乙烷或在氩气中进行γ射线照射灭菌。
