Kreft B, Layer G, Kuhl C, Sommer T, Gieseke J, Schild H
Radiologische Klinik, Universität Bonn.
Rofo. 1995 Nov;163(5):411-6. doi: 10.1055/s-2007-1016018.
The value of T2 weighted turbo-spin-echo sequences with selective fat suppression (TSE-SPIR) in the detection and differential diagnosis of focal liver lesions was compared to TSE sequences and conventional T1 weighted spin-echo (T1 SE) sequences at 0.5T.
In 50 patients with focal liver lesions T1 SE-TSE-, and TSE-SPIR sequences were performed. Two independent readers evaluated the sequences with regard to the image quality, fat suppression, and the number and conspicuity of liver lesions. Quantitative analysis was performed by tumour-liver contrast-to-noise (CNR) measurements.
From a total of 118 liver lesions the T1 SE sequence, the TSE sequence, and the TSE-SPIR sequence showed 85.6%, 83.9%, and 91.5%, respectively (p < 0.05). The tumour-liver CNR of malignant liver lesions was 30.2-46.6% higher on the TSE-SPIR sequence compared to the TSE sequence (p < 0.01). With the exception of fat-containing lesions there was no significant difference of CNR in benign lesions on both TSE sequences.
With regard to lesion detection the TSE-SPIR sequence is superior to the TSE sequence without fat suppression, whereas it is inferior to the TSE sequence in the differential diagnosis of benign and malignant lesions.
在0.5T条件下,将具有选择性脂肪抑制功能的T2加权快速自旋回波序列(TSE-SPIR)与TSE序列及传统T1加权自旋回波(T1 SE)序列在肝脏局灶性病变的检测及鉴别诊断中的价值进行比较。
对50例肝脏局灶性病变患者进行T1 SE、TSE及TSE-SPIR序列检查。两名独立阅片者对序列的图像质量、脂肪抑制效果以及肝脏病变的数量和清晰度进行评估。通过肿瘤-肝脏对比噪声(CNR)测量进行定量分析。
在总共118个肝脏病变中,T1 SE序列、TSE序列和TSE-SPIR序列的显示率分别为85.6%、83.9%和91.5%(p<0.05)。与TSE序列相比,TSE-SPIR序列上恶性肝脏病变的肿瘤-肝脏CNR高30.2-46.6%(p<0.01)。除含脂肪病变外,两种TSE序列在良性病变的CNR方面无显著差异。
在病变检测方面,TSE-SPIR序列优于未进行脂肪抑制的TSE序列,而在良性和恶性病变的鉴别诊断中,TSE-SPIR序列不如TSE序列。