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良性颅内高压:原发性抗磷脂综合征的非血栓性并发症?

Benign intracranial hypertension: a non-thrombotic complication of the primary antiphospholipid syndrome?

作者信息

Orefice G, De Joanna G, Coppola M, Brancaccio V, Ames P R

机构信息

Second Department of Neurology, Federico II University, Naples, Italy.

出版信息

Lupus. 1995 Aug;4(4):324-6. doi: 10.1177/096120339500400417.

DOI:10.1177/096120339500400417
PMID:8528233
Abstract

Benign intracranial hypertension is a rare complication of systemic lupus erythematosus often attributed to cerebral sinus thrombosis which impairs venous drainage and cerebrospinal fluid outflow. We report the case of a woman with a primary antiphospholipid syndrome who developed benign intracranial hypertension with no actual evidence of venous cerebral thrombosis and with no other possible cause for this clinical manifestation than high titres of anticardiolipin antibodies and a lupus anticoagulant.

摘要

良性颅内高压是系统性红斑狼疮的一种罕见并发症,常归因于脑静脉窦血栓形成,后者会损害静脉引流和脑脊液流出。我们报告了一例原发性抗磷脂综合征女性患者,该患者出现了良性颅内高压,但并无脑静脉血栓形成的实际证据,且除了高滴度抗心磷脂抗体和狼疮抗凝物外,没有其他可能导致这种临床表现的原因。

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Alterations in the cerebral venous circulation as a cause of headache.脑静脉循环改变作为头痛的一个原因。
Neurol Sci. 2009 May;30 Suppl 1:S7-10. doi: 10.1007/s10072-009-0052-8.
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Antiphospholipid syndrome and vascular ischemic (occlusive) diseases: an overview.抗磷脂综合征与血管性缺血(闭塞性)疾病:综述
Yonsei Med J. 2007 Dec 31;48(6):901-26. doi: 10.3349/ymj.2007.48.6.901.
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A case of multiple cranial nerve palsies as the initial ophthalmic presentation of antiphospholipid syndrome.一例以多发性颅神经麻痹为抗磷脂综合征首发眼科表现的病例。
Korean J Ophthalmol. 2006 Mar;20(1):76-8. doi: 10.3341/kjo.2006.20.1.76.
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Polyclonal B-cell expansion in the cerebrospinal fluid of patients with pseudotumor cerebri.假性脑瘤患者脑脊液中的多克隆B细胞扩增。
J Clin Immunol. 2004 Nov;24(6):674-82. doi: 10.1007/s10875-004-6242-5.