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[韩国济州岛的胃异尖线虫病病例]

[Gastric anisakiasis cases in Cheju-do, Korea].

作者信息

Im K I, Shin H J, Kim B H, Moon S I

机构信息

Institute of Tropical Medicine, College of Medicine, Yonsei University, Seoul, Korea.

出版信息

Korean J Parasitol. 1995 Sep;33(3):179-86. doi: 10.3347/kjp.1995.33.3.179.

Abstract

Human anisakiasis may occur after ingestion of raw marine fish infected with nematode larvae of Anisakidae. Anisakiasis caused by the migration of the larva into the wall of stomach, small intestine and other portion has been reported in Korea. This prospective study was made of all cases referred to parasitological laboratory in Cheju-do between June 1989 and June 1992. Gastric anisakiasis was confirmed if larvae invading the gastric wall were observed by gastrofiberscopy. One hundred and seven cases were diagnosed, most of which were in 30-49 years old. Most of the patients complained acute epigastric pain with history of eating raw marine fish. This symptom usually occurred about 12 hours to 1 day after ingestion of infected marine fish. Edema, erosion or ulcer of the mucosa and hemorrhage from the gastric wall were observed in the involved areas. Ninety larvae removed from the stomach were identified; the larva of Anisakis simplex was the most prevalent species, and the larva of Pseudoterranova decipiens was also detected. The important species of marine fish from which the patients became infected was demonstrated as yellow corvina, sea eel, ling, cuttle fish, yellowtail and others. Five species of marine fish as a possible source of infection were examined, and Anisakis simplex larvae and Pseudoterranova decipiens larvae were collected from the mackerel and rock cod. This study demonstrates that anisakiasis is recognized as a public health problem in Korea.

摘要

人体异尖线虫病可能在摄入感染异尖科线虫幼虫的生海鱼后发生。由幼虫迁移至胃壁、小肠壁及其他部位引起的异尖线虫病在韩国已有报道。本前瞻性研究针对1989年6月至1992年6月间转诊至济州岛寄生虫学实验室的所有病例展开。若通过纤维胃镜观察到幼虫侵入胃壁,则确诊为胃异尖线虫病。共诊断出107例病例,其中大多数患者年龄在30至49岁之间。大多数患者主诉有食用生海鱼史后出现急性上腹部疼痛。这种症状通常在摄入受感染海鱼后约12小时至1天出现。在受累区域观察到黏膜水肿、糜烂或溃疡以及胃壁出血。从胃中取出的90条幼虫得到鉴定;简单异尖线虫幼虫最为常见,也检测到了欺骗新地蛔线虫幼虫。已证实患者感染的重要海鱼种类有黄鳍鲷、海鳗、鳕鱼、乌贼、黄尾鱼等。对5种可能作为感染源的海鱼进行了检查,从鲭鱼和石斑鱼中采集到了简单异尖线虫幼虫和欺骗新地蛔线虫幼虫。本研究表明,异尖线虫病在韩国被视为一个公共卫生问题。

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