Kirejczyk J K, Debek W, Dziecioł J, Chyczewski L, Makarewicz M, Nikliński J
Department of Pediatric Surgery, Medical Academy of Bialystok.
Rocz Akad Med Bialymst. 1995;40(1):77-87.
Renal damage in rat hemorrhagic shock model was assessed by estimation of the reactive oxygen metabolites generation (malondialdehyde measured as thiobarbituric acid reactive substances) and antioxidative potential (activity of Cu-, Zn- superoxide dismutase, activity of glutathione reductase and level of sulfhydryl compounds). It was found that treatment with BN 52021 (a platelet-activating factor antagonist), and polyelektrolyte solution had had a beneficial effect in comparison with both the untreated shock and shock treated by reperfusion only.
