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哺乳期南象海豹(Mirounga leonina)乳汁中的免疫球蛋白A水平。

Immunoglobulin A levels in southern elephant seal (Mirounga leonina) milk during the suckling period.

作者信息

Marquez M E, Slobodianik N H, Ronayne de Ferrer P A, Carlini A R, Vergani D F, Daneri G A

机构信息

Department of Biological Sciences, Argentine Antarctic Institute, Buenos Aires, Argentina.

出版信息

Comp Biochem Physiol B Biochem Mol Biol. 1995 Nov;112(3):569-72. doi: 10.1016/0305-0491(95)00101-8.

DOI:10.1016/0305-0491(95)00101-8
PMID:8529033
Abstract

Immunoglobulin A (IgA) levels in milk samples from southern elephant seals at King George Island, Antarctica are reported. IgA levels were determined throughout the suckling period (approximately 23 days). The IgA concentration in southern elephant seal milk was lower than in other mammals and, unlike most mammalian milk, was not high during early lactation. There was not a definite pattern in IgA levels, which fluctuated within narrow limits throughout the suckling period (mean +/- SD, 30.81 +/- 6.38 mg IgA/100 g milk). If IgG was present, its level was too low to be detected by the method used. This is the first evidence in Southern elephant seal of the possibility of transmission of passive immunity after birth involving secretion of IgA in the milk.

摘要

报告了南极乔治王岛南象海豹乳汁样本中的免疫球蛋白A(IgA)水平。在整个哺乳期(约23天)测定了IgA水平。南象海豹乳汁中的IgA浓度低于其他哺乳动物,并且与大多数哺乳动物的乳汁不同,在哺乳初期并不高。IgA水平没有明确的模式,在整个哺乳期内都在狭窄范围内波动(平均值±标准差,30.81±6.38毫克IgA/100克乳汁)。如果存在IgG,其水平过低,无法用所用方法检测到。这是南象海豹出生后通过乳汁分泌IgA进行被动免疫传递可能性的首个证据。

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