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Protein-tyrosine phosphatase SH-PTP2 (PTPN11) is localized to 12q24.1-24.3.

作者信息

Dechert U, Duncan A M, Bastien L, Duff C, Adam M, Jirik F R

机构信息

Department of Medicine, University of British Columbia, Vancouver, Canada.

出版信息

Hum Genet. 1995 Nov;96(5):609-15. doi: 10.1007/BF00197421.

DOI:10.1007/BF00197421
PMID:8530013
Abstract

A 2.1-kb cDNA probe encoding the human SH2-domain containing protein-tyrosine phosphatase SH-PTP2 (PTPN11) was hybridized to human metaphase chromosomes in three independent experiments. In each instance, hybridization was maximal to chromosome 12q24.1-q24.3. The presence of SH-PTP2 cDNA crosshybridizing sequences located on a number of other chromosomes suggested that SH-PTP2-related genes or pseudogenes are present in the human genome.

摘要

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本文引用的文献

1
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Chromosomal localization of an SH2 containing tyrosine phosphatase (SH-PTP3) gene to chromosome 12q24.1.含SH2结构域的酪氨酸磷酸酶(SH-PTP3)基因在染色体12q24.1上的染色体定位。
Oncogene. 1994 Jun;9(6):1751-3.
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Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.
变构抑制通过单细胞转录组学揭示了SHP2介导的结肠癌肿瘤免疫抑制作用。
Acta Pharm Sin B. 2022 Jan;12(1):149-166. doi: 10.1016/j.apsb.2021.08.006. Epub 2021 Aug 11.
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Prolonged thrombocytopenia in a neonate with Noonan syndrome: a case report.一名患有努南综合征的新生儿出现持续性血小板减少症:病例报告。
J Int Med Res. 2020 Aug;48(8):300060520936445. doi: 10.1177/0300060520936445.
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Genetic Polymorphisms Associated with the Neutrophil⁻Lymphocyte Ratio and Their Clinical Implications for Metabolic Risk Factors.与中性粒细胞-淋巴细胞比值相关的基因多态性及其对代谢危险因素的临床意义
J Clin Med. 2018 Aug 8;7(8):204. doi: 10.3390/jcm7080204.
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[Spectrum of somatic mutations and their prognostic significance in adult patients with B cell acute lymphoblastic leukemia].[成人B细胞急性淋巴细胞白血病体细胞突变谱及其预后意义]
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Genetics of Bladder Malignant Tumors in Childhood.儿童膀胱恶性肿瘤的遗传学
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小鼠含SH2结构域的磷酸酪氨酸磷酸酶Syp的受体结合、酪氨酸磷酸化及染色体定位
Oncogene. 1994 Jun;9(6):1545-50.
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Science. 1993 Mar 12;259(5101):1607-11. doi: 10.1126/science.8096088.
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