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诊断检查的整合以及门诊手术在乳腺疾病管理中的作用。

The integration of diagnostic tests and the role of outpatient surgery in the management of breast disease.

作者信息

Ranieri E, D'Andrea M R, D'Alessio A, Bergomi S, Virno F

机构信息

Service of Diagnosis, Prevention and Treatment of Tumors, Policlinico Umberto I, La Sapienza University, Rome, Italy.

出版信息

Int Surg. 1995 Apr-Jun;80(2):181-4.

PMID:8530240
Abstract

The aim of the earliest possible diagnosis of breast carcinoma achieved through the integration of clinical, mammographic, sonographic and cytologic data has determined an increased detection of breast lesions and a greater accuracy in their description. Nevertheless, the nature of some of these lesions cannot be well-defined because of their biological characteristics and their physical, radiological or cytological aspects. The need to obtain a definitive diagnosis in any case has given rise to a paradoxical increase in histologic examinations: in specific conditions and for certain kinds of lesions, outpatient surgery under local anesthesia could very well represent a supplementary tool in the diagnostic and therapeutic strategy for the management of breast lesions. The data here reported concern 397 breast lesions for which it was thought appropriate to complete the diagnostic procedure with the surgical excision on an outpatient basis under local anesthesia. Excluding the 3 breast lymphomas and the 19 loco-regional recurrences, for which the purpose of outpatient surgery was therapeutic, at the histologic examination 35% benign lesions, of which 91 associated with an increased risk of breast cancer, were found, as well as 11 in situ and 10 invasive carcinomas (false negatives), with a therapeutic option error of 2.5%. Now that one of the principal aims of public management is to put a check on health expenditures, outpatient surgery would contribute to obtaining the correct balance between proper management of breast lesions and low cost/effective ratio.

摘要

通过整合临床、乳腺X线摄影、超声和细胞学数据实现乳腺癌尽早诊断的目标,已使乳腺病变的检出率提高,且对病变的描述准确性更高。然而,由于其中一些病变的生物学特性及其物理、放射学或细胞学方面的特征,其性质无法明确界定。无论如何都需要获得明确诊断,这导致组织学检查出现了反常的增加:在特定情况下和对于某些类型的病变,局部麻醉下的门诊手术很可能成为乳腺病变管理的诊断和治疗策略中的一种辅助手段。此处报告的数据涉及397例乳腺病变,认为对这些病变在局部麻醉下进行门诊手术切除以完成诊断程序是合适的。排除3例乳腺淋巴瘤和19例局部区域复发(门诊手术的目的是治疗性的),在组织学检查中发现35%为良性病变,其中91例与乳腺癌风险增加相关,还有11例原位癌和10例浸润性癌(假阴性),治疗选择错误率为2.5%。鉴于公共管理的主要目标之一是控制医疗费用,门诊手术将有助于在乳腺病变的合理管理与低成本/效益比之间取得正确平衡。

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