Sadamatsu K, Harasawa Y, Ozono K, Yasutsune T, Masuda M, Kawachi Y, Yasui H, Takeshita A
Division of Cardiology, Kyushu University Medical School, Fukuoka, Japan.
Heart Vessels. 1995;10(4):218-20. doi: 10.1007/BF01744990.
We describe a case of large ventricular septal defect (VSD) with minimal obstructive changes in the small pulmonary arteries of a 41-year-old woman. Before cardiac catheterization, some laboratory findings led us to consider that surgical closure of the defect would not be possible. However, because hemodynamic examinations showed only mildly elevated pulmonary vascular resistance, we patch-closed the VSD successfully. The histology of lung specimens showed only minimal obstructive changes in the small pulmonary arteries. Considering the size of the VSD and the age at which we hemodynamically evaluated the patient, the mildness of the pulmonary vascular obstructive changes appeared to be atypical in the natural course of a VSD of this size.
我们描述了一例41岁女性的大型室间隔缺损（VSD）病例，其小肺动脉仅有轻微的阻塞性改变。在进行心导管检查之前，一些实验室检查结果使我们认为无法进行手术闭合缺损。然而，由于血流动力学检查显示肺血管阻力仅轻度升高，我们成功地对室间隔缺损进行了补片闭合。肺标本的组织学检查显示小肺动脉仅有轻微的阻塞性改变。考虑到室间隔缺损的大小以及我们对患者进行血流动力学评估时的年龄，这种大小的室间隔缺损自然病程中肺血管阻塞性改变的轻微程度似乎不典型。
