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使用氮敏感火焰离子化检测器气相色谱法测定全血和血浆中的可卡因。

Gas chromatographic determination of cocaine in whole blood and plasma using a nitrogen-sensitive flame ionization detector.

作者信息

Dvorchik B H, Miller S H, Graham W P

出版信息

J Chromatogr. 1977 May 11;135(1):141-8. doi: 10.1016/s0021-9673(00)86310-4.

Abstract

A procedure is described for the determination of as little as 20 ng of cocaine from 1 ml of whole blood or plasma. Methods are also given for the storage of whole blood or plasma containing cocaine as well as for whole blood or plasma extracts. Blood levels in patients receiving intranasal cocaine for topical anesthesia while undergoing rhinoplasty are also presented.

摘要

本文描述了一种从1毫升全血或血浆中测定低至20纳克可卡因的方法。文中还给出了含有可卡因的全血或血浆以及全血或血浆提取物的储存方法。此外,还展示了接受鼻内可卡因用于隆鼻手术局部麻醉的患者的血药浓度。

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