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采用氮敏感检测器测定血浆中阿米替林和去甲替林的快速、灵敏的气液色谱法。

Rapid, sensitive gas-liquid chromatographic method for determination of amitryptyline and nortriptyline in plasma using a nitrogen-sensitive detector.

作者信息

Hucker H B, Stauffer S C

出版信息

J Chromatogr. 1977 Aug 11;138(2):437-42. doi: 10.1016/s0021-9673(00)94979-3.

Abstract

A simple gas chromatographic method for determination of amitriptyline and nortriptyline in plasma using a nitrogen-sensitive detector is described. Concentrations of both drugs as low as 10 ng per ml plasma were measured. The precision and accuracy of the method are within acceptable limits.

摘要

描述了一种使用氮敏感检测器测定血浆中阿米替林和去甲替林的简单气相色谱法。测定了血浆中低至每毫升10纳克的两种药物浓度。该方法的精密度和准确度在可接受范围内。

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