Rao K V, Diaz R, Quigley T J
J Am Geriatr Soc. 1977 May;25(5):230-1. doi: 10.1111/j.1532-5415.1977.tb00304.x.
Procainamide-induced systemic lupus erythematosus (SLE) is a well recognized clinical syndrome believed to be characterized by normocomplementemia. However, in 7 cases of drug-induced SLE recorded in the literature, hypocomplementemia was found. The present report concerns a well documented case of procainamide-induce SLE with hypocomplementemia. The patient improved and complement values returned to normal after procainamide therapy was discontinued and replaced by digitalis and steroid therapy.
普鲁卡因胺诱发的系统性红斑狼疮（SLE）是一种公认的临床综合征，一般认为其特征为补体正常。然而，文献记载的7例药物性SLE病例中发现有补体降低。本报告涉及1例记录完整的普鲁卡因胺诱发的SLE伴补体降低的病例。停用普鲁卡因胺并换用地高辛和类固醇治疗后，患者病情改善，补体值恢复正常。
