Green G, Gow P J
Rheumatology Department, Middlemore Hospital, Otahuhu, Auckland.
N Z Med J. 1995 Dec 8;108(1013):512-4.
To determine the intralaboratory and interlaboratory variation in reported ANA titres in three Auckland laboratories, and to see if this has improved since a similar study was performed in 1981.
Serum samples on 26 subjects with rheumatological symptoms were sent to the three laboratories on two separate days in 1993, and the presence and titre of ANA determined.
The number of titre dilutions by which duplicate samples differed within each laboratory has decreased since the previous study, and variation within each laboratory of greater than two dilutions was not observed. The correlation between the laboratories has improved since the previous study, particularly for Lab A vs. Lab B.
The ANA test, as expressed in titres, is more reproducible in Auckland laboratories than has been the case in the past.
确定奥克兰三家实验室报告的抗核抗体（ANA）滴度的实验室内和实验室间差异，并观察自1981年进行类似研究以来情况是否有所改善。
1993年，将26名有风湿症状患者的血清样本分两天送至这三家实验室，并检测ANA的存在情况和滴度。
自上次研究以来，各实验室内重复样本之间滴度稀释倍数的差异数量有所减少，且未观察到各实验室内有超过两个稀释倍数的差异。自上次研究以来，各实验室之间的相关性有所改善，尤其是实验室A与实验室B之间。
以滴度表示的ANA检测在奥克兰的实验室中比过去具有更高的可重复性。
