McCouch S R, Doerge R W
Department of Plant Breeding and Biometry, Cornell University, Ithaca, NY 14853, USA.
Trends Genet. 1995 Dec;11(12):482-7. doi: 10.1016/s0168-9525(00)89157-x.
In the past 10 years, interest in applying the tools of molecular genetics to the problem of increasing world rice production has resulted in the generation of two highly saturated, molecular linkage maps of rice, and the localization of numerous genes and quantitative trait loci (QTLs). Primary studies have identified QTLs associated with disease resistance, abiotic stress tolerance and yield potential of rice in a range of ecosystems. The ability to identify, manipulate and potentially clone individual genes involved in quantitatively inherited characters, combined with the demonstrated conservation of numerous linkage blocks among members of the grass family, emphasizes the contribution of map-based genetic analyses both to applied and to basic crop research.
在过去十年中,人们对运用分子遗传学工具解决全球水稻增产问题的兴趣,催生了两张饱和度极高的水稻分子连锁图谱,并对众多基因和数量性状位点(QTL)进行了定位。初步研究已在一系列生态系统中确定了与水稻抗病性、非生物胁迫耐受性和产量潜力相关的QTL。识别、操纵并有可能克隆涉及数量遗传性状的单个基因的能力,再加上禾本科成员间众多连锁区段的保守性,凸显了基于图谱的遗传分析对应用作物研究和基础作物研究的贡献。