Hashimoto T, Sasagawa I, Ishigooka M, Kubota Y, Nakada T, Fujita T, Nakai O
Department of Urology, Yamagata University, School of Medicine, Japan.
Urol Int. 1995;55(2):120-2. doi: 10.1159/000282766.
In patients with Down's syndrome, the frequency of leukemia is significantly greater than normally would be expected. However, cancers other than leukemia have been reported to occur rarely. We present a case of Down's syndrome associated with intracranial germinoma and testicular embryonal carcinoma. Currently, no case of double primary carcinomas in Down's syndrome has been reported to the authors' knowledge.