Lamb C R, Simpson K W, Boswood A, Matthewman L A
Queen Mother Hospital for Animals, Department of Small Animal Medicine and Surgery, Royal Veterinary College, University of London, North Mymms, Hertfordshire.
Vet Rec. 1995 Jul 15;137(3):65-8. doi: 10.1136/vr.137.3.65.
The history, clinical signs and radiographic and ultrasonographic findings in 16 dogs with pancreatic neoplasia were reviewed retrospectively. Thirteen of the dogs had islet cell carcinoma compatible with insulinoma, one had a pancreatic adenocarcinoma and two had secondary invasion of the pancreas, one by a gastric carcinoma and one by an intestinal lymphoma. The clinical signs in the 13 dogs with insulinoma included collapse in 10 dogs, ataxia in seven, weakness in five, and seizures in two. Two of the 16 dogs had jaundice due to biliary obstruction by the primary tumour or metastases. The sensitivities for pancreatic neoplasia were three of 16 (19 per cent) for radiography and 12 of 16 (75 per cent) for ultrasonography; the sensitivities for metastasis were two of 11 (18 per cent) for radiography and six of 11 (55 per cent) for ultrasonography. Biliary obstruction was detected by ultrasonography in both affected dogs.
对16只患有胰腺肿瘤的犬的病史、临床症状以及影像学和超声检查结果进行了回顾性研究。其中13只犬患有与胰岛素瘤相符的胰岛细胞瘤,1只患有胰腺腺癌,2只胰腺有继发性浸润,1例由胃癌引起,1例由肠道淋巴瘤引起。13只患有胰岛素瘤的犬的临床症状包括10只犬虚脱、7只共济失调、5只虚弱、2只癫痫发作。16只犬中有2只因原发性肿瘤或转移瘤导致胆管阻塞而出现黄疸。胰腺肿瘤的X线敏感性为16只中的3只(19%),超声检查为16只中的12只(75%);转移瘤的X线敏感性为11只中的2只(18%),超声检查为11只中的6只(55%)。两只患病犬均通过超声检查发现胆管阻塞。