Danilov A B, Poliakova N F, Shvareva I S, Sadekov R K, Oknin V Iu
Zh Nevrol Psikhiatr Im S S Korsakova. 1995;95(4):80-2.
The case of idiopathic orthostatic hypotension (Bradbury-Eggleston syndrome) which gradually arose in 70-years-old women was described. The clinical pattern of syndrome included pronounced orthostatic hypotension, fixed constant rare pulse (46-56 per minutes), independent of the changes in body position together with hypohidrosis and constipation. Autonomic nervous system investigation carried out with the help of the cardiovascular tests, spectral analysis of heart rhythm as well as sympathetic skin potential revealed expressed disturbances in autonomic functions of cardiovascular and sudomotor systems. Peculiarity of the case was the development of disease on the background of drug-compensated hypothyreosis which was not however the cause of progressive autonomic disorders in patient.
描述了一名70岁女性逐渐出现的特发性直立性低血压(布拉德伯里 - 埃格尔斯顿综合征)病例。该综合征的临床症状包括明显的直立性低血压、固定不变的缓慢脉搏(每分钟46 - 56次),与体位变化无关,同时伴有少汗和便秘。借助心血管测试、心律频谱分析以及交感神经皮肤电位对自主神经系统进行的检查显示,心血管和汗腺运动系统的自主功能存在明显紊乱。该病例的特殊之处在于,疾病是在药物代偿性甲状腺功能减退的背景下发生的,但这并非患者进行性自主神经障碍的原因。