Oyelami O A, Maxwell S M, Aladekomo T A, Adelusola K A
Department of Paediatrics and Child Health, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
Ann Trop Paediatr. 1995 Sep;15(3):217-9. doi: 10.1080/02724936.1995.11747775.
Two children with unusual features of kwashiorkor are reported. One, an exclusively breastfed 7-month-old girl, had been admitted earlier, treated for pneumonia and discharged 3 weeks before she presented with kwashiorkor. The other was an identical twin who was admitted for kwashiorkor and gastro-enteritis. The twin sister was underweight but relatively well. Both children died. Potent aflatoxins were detected in the organs of these children on post-mortem examination. The occurrence of kwashiorkor in a fully breastfed infant and in an identical twin does not accord with the extant belief that the aetiology of kwashiorkor is wholly nutritional, but suggests a disease probably of multifactorial origin.
报告了两名患有恶性营养不良独特症状的儿童。一名是纯母乳喂养的7个月大女孩，此前曾因肺炎入院治疗，在出现恶性营养不良症状前三周出院。另一名是同卵双胞胎，因恶性营养不良和肠胃炎入院。双胞胎姐妹体重不足但相对健康。两名儿童均死亡。尸检时在这些儿童的器官中检测到强效黄曲霉毒素。纯母乳喂养婴儿和同卵双胞胎中出现恶性营养不良，这与目前认为恶性营养不良病因完全是营养性的观点不符，而是提示这可能是一种多因素起源的疾病。
