Celko A M
Department of Epidemiology, 3rd Medical Faculty, Charles University, Prague, Czech Republic.
Cent Eur J Public Health. 1995 Aug;3(3):119-23.
Carcinoma of the prostate is the second most common cancer and fourth most common cause of death from cancer, among men in Czech Republic. Of all tumours, the prevalence of prostate cancer increases the most rapidly with age. A shift in age distribution favouring the older population as a consequence of health promotion and disease prevention programmes, will lead to a permanent increase in the number of patients diagnosed with prostate cancer in Czech males. Its incidence is raising steadily and about 2/3 of all new cases are diagnosed at the time of extra-prostatic or distant disease with poor prognosis for cure. Current evidence especially from the USA strongly suggests that combing the improving prostate-specific antigen test (Hybritech Tandem assay) with the digital rectal examination increases the early detection rate for prostate cancer. Implementation of this scheme to routine diagnostics can offer the best chance of increased survival, decreased morbidity and possible cure of the Czech males.
在捷克共和国男性中，前列腺癌是第二常见的癌症，也是第四大常见癌症死因。在所有肿瘤中，前列腺癌的患病率随年龄增长上升最为迅速。由于健康促进和疾病预防计划，年龄分布向老年人群偏移，这将导致捷克男性中被诊断出前列腺癌的患者数量持续增加。其发病率在稳步上升，大约三分之二的新病例是在前列腺外或远处疾病阶段被诊断出来的，治愈预后较差。目前尤其是来自美国的证据有力地表明，将改进后的前列腺特异性抗原检测（Hybritech串联检测法）与直肠指检相结合，可提高前列腺癌的早期检测率。将该方案应用于常规诊断可为提高捷克男性的生存率、降低发病率以及实现可能的治愈提供最佳机会。
