Chang K J
University of California Irvine Medical Center, Orange, USA.
Gastrointest Endosc Clin N Am. 1995 Oct;5(4):723-34.
Endoscopic ultrasound (EUS) is useful in the detection of pancreatic carcinoma. One of its major limitations is the lack of specificity for malignancy, both for the primary tumor and for associated lymph nodes due to its inability to distinguish malignant infiltration from benign inflammation. EUS-guided fine needle aspiration (FNA) has now been developed, which allows for a tissue diagnosis of the primary tumor as well as lymph nodes, liver metastasis, and peritoneal/pleural fluid. The addition of EUS-guided FNA, with the specificity of a tissue diagnosis, to the high sensitivity and vascular assessment of EUS alone makes this the modality of choice for the diagnosis and staging of pancreatic carcinoma. The results of preliminary studies along with discussion regarding the technique, safety, cytologic adequacy, diagnostic accuracy, clinical utility, and future trends of EUS-guided FNA in pancreatic tumors are presented.
内镜超声（EUS）在胰腺癌的检测中很有用。其主要局限性之一是对恶性肿瘤缺乏特异性，无论是对原发性肿瘤还是相关淋巴结，因为它无法区分恶性浸润和良性炎症。目前已开发出EUS引导下细针穿刺抽吸术（FNA），它可对原发性肿瘤以及淋巴结、肝转移和腹膜/胸水进行组织诊断。将具有组织诊断特异性的EUS引导下FNA与单独EUS的高敏感性和血管评估相结合，使其成为胰腺癌诊断和分期的首选方式。本文介绍了关于EUS引导下FNA在胰腺肿瘤中的技术、安全性、细胞学充分性、诊断准确性、临床实用性及未来趋势的初步研究结果和讨论。
