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[缺血性心脏病心绞痛发作时的心肌收缩力]

[Myocardial contractility during angina pectoris attack in ischemic heart disease].

作者信息

Krol V A, Iurenev A P, Belenkov Iu N, At'kov O Iu, Fomina G A

出版信息

Kardiologiia. 1977 Jan;17(1):85-9.

PMID:853602
Abstract

The myocardial contractility function was studied with the aid of echocardiography in 42 male patients during dosaged physical exercises. The patients were selected so that at the peak of the exercises they developed an angina pectoris attack documented by ischaemic ECG changes. In some of the patients the changes were also observed during attacks of angina decubitus. Anginal attacks are accompanied by a reduction of the myocardial function. Haemodynamic reactions of two types were noted with myocardial ischaemia: type I reaction was observed in patients with ischaemic heart disease and practically normal values of the initial heart volume, and consisted in an increasing end-systolic and end-diastolic volumes, with the stroke volume remaining unchanged, and the ejection fraction somewhat decreasing; type 2 reaction was observed in patients with initially increased heart volumes, and consisted in a decreasing end-diastolic and stroke volumes, with an insignificant alteration of the end-systolic volume. The ejection fraction, being initially insignificantly decreased, tends to decrease further during the attack.

摘要

在42名男性患者进行定量体育锻炼期间,借助超声心动图对其心肌收缩功能进行了研究。选择这些患者,以便在运动高峰时他们出现由缺血性心电图变化记录的心绞痛发作。在一些患者中,在卧位型心绞痛发作期间也观察到了这些变化。心绞痛发作伴有心肌功能降低。心肌缺血时观察到两种类型的血流动力学反应:I型反应见于缺血性心脏病且初始心脏容积实际正常的患者,表现为收缩末期和舒张末期容积增加,而每搏输出量保持不变,射血分数略有下降;2型反应见于初始心脏容积增加的患者,表现为舒张末期和每搏输出量减少,收缩末期容积变化不明显。射血分数起初略有下降,在发作期间趋于进一步降低。

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