Cohen L, Bachoud-Levi A C
Service de Neurologie, Hôpital de la Salpêtrière, Paris.
Cortex. 1995 Sep;31(3):469-86. doi: 10.1016/s0010-9452(13)80060-3.
A patient with a selective impairment of speech output, associating phonemic paraphasias and pervasive preverbal pauses, it is described. Experimental data are discussed in relation to current models of speech production. On clinical evaluation, the pattern of paraphasias was strongly suggestive of a functional lesion affecting the output phonological buffer. This hypothesis received substantial support from a study of word and non-word repetition, as well as from a study of picture naming latencies, with various imposed delays between stimulus presentation and vocal response. In order to determine the origin of the preverbal pauses, the patient was also submitted to other timed motor tasks implicity probing higher levels of word production (gender decision and phonemic matching). We suggest that the pauses probably resulted from the conjunction of several mechanisms, including a general slowing apparent in all timed motor tasks, as well as a more specific time lag in speech initiation originating from the output buffer or from the articulator itself.
本文描述了一名存在言语输出选择性障碍的患者，伴有音素性错语和普遍存在的言语前停顿。结合当前的言语产生模型对实验数据进行了讨论。临床评估显示，错语模式强烈提示存在影响输出语音缓冲器的功能性损伤。这一假设得到了单词和非单词重复研究以及图片命名潜伏期研究的有力支持，这些研究在刺激呈现和发声反应之间设置了不同的延迟。为了确定言语前停顿的根源，还让该患者进行了其他计时运动任务，这些任务隐含地探测了更高水平的单词产生（性别判断和音素匹配）。我们认为，这些停顿可能是由多种机制共同作用导致的，包括所有计时运动任务中普遍出现的动作迟缓，以及源自输出缓冲器或发音器官本身的言语起始更特定的时间延迟。
