Theodossiadis P, Kokolakis S, Ladas I, Kollia A C, Chatzoulis D, Theodossiadis G
Department of Ophthalmology, School of Medicine, Athens University, Greece.
Int Ophthalmol. 1995;19(1):19-24. doi: 10.1007/BF00156414.
The present study deals with the retinal vascular involvement in 64 patients with toxoplasmic retinochoroiditis during the acute phase of the disease and its evolution. Vascular involvement was noted in all 64 eyes during the acute phase of the disease. In 59 (92%) out of 64 cases the vascular involvement was located in the same retinal quadrant as the active toxoplasmic lesion. In the remaining 5 eyes (8%) the vascular participation was found in all four retinal quadrants. In 3 (5%) out of 64 cases, the vascular infiltration was extremely severe and resulted in retinal vascular obstruction. In all three cases the vessel traversed the active toxoplasmic lesion. In 35 (55%) out of 64 patients the initial vascular picture changed in the course of the acute phase of the disease. In these patients, the lesions had extended to the adjacent vessels or to other parts of the involved vessel. In the further course of the evolution of the active toxoplasmic lesion, the vascular involvement did not persist indiscriminately. It was noted that in 14 (22%) out of 64 cases the vascular lesions gradually regressed and eventually disappeared together with the active toxoplasmic lesion and the formation of the retinochoroidal scar. In the remaining 50 (78%) out of 64 cases the vascular involvement either disappeared after the establishment of the retinochoroidal scar in 3-12 months (29 cases) or remained permanently (21 cases).
本研究探讨了64例急性弓形体性视网膜脉络膜炎患者在疾病急性期及病情发展过程中的视网膜血管受累情况。在疾病急性期,所有64只眼均发现有血管受累。64例中有59例(92%)血管受累位于与活动性弓形体病灶相同的视网膜象限。其余5只眼(8%)的血管受累见于所有四个视网膜象限。64例中有3例(5%)血管浸润极为严重,导致视网膜血管阻塞。在所有这三例中,血管均穿过活动性弓形体病灶。64例患者中有35例(55%)在疾病急性期血管情况发生了变化。在这些患者中,病灶已扩展至相邻血管或受累血管的其他部位。在活动性弓形体病灶进一步发展过程中,血管受累并非持续存在。值得注意的是,64例中有14例(22%)血管病变逐渐消退,最终与活动性弓形体病灶及视网膜脉络膜瘢痕的形成一起消失。在64例中其余50例(78%)血管受累情况,要么在3至12个月视网膜脉络膜瘢痕形成后消失(29例),要么持续存在(21例)。