Cheitlin M D
Med Clin North Am. 1977 May;61(3):655-73. doi: 10.1016/s0025-7125(16)31323-2.
Coarctation of the aorta is a cause of hypertension that can present dramatically in the severely ill infant or appear incidentally in the asymptomatic young adult. Coarctation is easily detected and there is good evidence that the extremely poor natural history can be altered favorably by surgical correction. The elevated blood pressure can be lowered in the majority of patients, and there is every expectation that the incidence of known complications of coarctation can be decreased. However, in about three fourths of the patients, significant residual cardiovascular defects persist, with their potential for future problems as yet incompletely defined. For this reason, patients who have undergone surgery for coarctation will need to be followed carefully for an indefinite period.
主动脉缩窄是导致高血压的一个原因,在重症婴儿中可能会显著表现出来,也可能在无症状的年轻成年人中偶然发现。主动脉缩窄很容易被检测出来,而且有充分的证据表明,通过手术矫正可以有利地改变极差的自然病程。大多数患者的血压可以降低,而且人们完全有理由期望主动脉缩窄已知并发症的发生率能够降低。然而,大约四分之三的患者仍存在显著的残余心血管缺陷,其未来出现问题的可能性尚未完全明确。因此,接受主动脉缩窄手术的患者需要在一段不确定的时间内接受仔细的随访。