Ustüner T E, Zhang F, Lineaweaver W C
Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, CA 94305, USA.
Microsurgery. 1995;16(8):533-5. doi: 10.1002/micr.1920160805.
Thrombosis rates of femoral end-to-end microvenous anastomoses with nylon and polypropylene sutures (9-0 suture, 70 mu needle) were compared in a microvenous thrombosis model. The vessel injuries were produced during anastomosis by using a suture with a knot 1 cm from the needle. Anastomotic thrombosis rates were assessed by visual inspection and strip test at 24 hr postoperatively. Low thrombosis rates (0% and 20%, respectively) of anastomoses with both unknotted nylon and unknotted polypropylene sutures were obtained. Anastomoses with knotted nylon and polypropylene sutures resulted in 65% and 45% thrombosis rates, respectively. Statistical analyses showed that there were no significant differences between thrombosis rates, both in anastomosis performance with unknotted nylon and polypropylene sutures (P > 0.05) and with knotted nylon and polypropylene sutures (P > 0.05), while there were significant differences between the thrombosis rate using unknotted sutures and knotted sutures (P < 0.01). It was concluded that vascular injury, not suture material, is the main factor leading to thrombosis in this model.
在一个微静脉血栓形成模型中，比较了使用尼龙和聚丙烯缝线（9-0缝线，70μm针）进行股静脉端端微血管吻合的血栓形成率。在吻合过程中，通过使用距针1cm处带有结的缝线造成血管损伤。术后24小时通过肉眼检查和条带试验评估吻合口血栓形成率。未打结的尼龙和未打结的聚丙烯缝线吻合的血栓形成率较低（分别为0%和20%）。打结的尼龙和聚丙烯缝线吻合的血栓形成率分别为65%和45%。统计分析表明，未打结的尼龙和聚丙烯缝线吻合的血栓形成率之间（P>0.05）以及打结的尼龙和聚丙烯缝线吻合的血栓形成率之间（P>0.05）均无显著差异，而使用未打结缝线和打结缝线的血栓形成率之间存在显著差异（P<0.01）。得出的结论是，在该模型中，血管损伤而非缝线材料是导致血栓形成的主要因素。
