Mukherji S K, Weeks S M, Castillo M, Yankaskas B C, Krishnan L A, Schiro S
Department of Radiology, University of North Carolina School of Medicine, Chapel Hill 27599-7510, USA.
Radiology. 1996 Jan;198(1):157-62. doi: 10.1148/radiology.198.1.8539370.
To determine the ability to use computed tomography (CT) to predict invasion of adjacent nerves or vessels by oral cavity tumors.
Contrast material-enhanced CT scans and histopathologic reports were retrospectively reviewed in 48 patients (36 men, 12 women) aged 38-75 years who underwent gross total resection of squamous cell carcinomas arising in the tongue, the base of the tongue, and the floor of the mouth. CT criteria for diagnosis of perineural or vascular invasion were aggressive tumor margins, invasion of the sublingual space, and direct adjacency of the tumor to the enhanced lingual vasculature in the sublingual space. CT and histopathologic findings of perineural and/or vascular invasion by tumor were correlated in all patients.
With the above criteria, CT findings predictive of perineural or vascular invasion had a sensitivity of 88%; specificity, 83%; positive predictive value, 85%; and negative predictive value, 84%.
CT findings can be used to predict perineural or vascular invasion by oral cavity tumors.
确定使用计算机断层扫描（CT）预测口腔肿瘤侵犯相邻神经或血管的能力。
回顾性分析48例年龄在38 - 75岁之间的患者（36例男性，12例女性）的对比增强CT扫描和组织病理学报告，这些患者均接受了舌、舌根和口底鳞状细胞癌的根治性切除术。诊断神经周围或血管侵犯的CT标准为肿瘤边缘浸润性、舌下间隙侵犯以及肿瘤与舌下间隙内强化的舌血管直接相邻。对所有患者肿瘤神经周围和/或血管侵犯的CT及组织病理学结果进行相关性分析。
根据上述标准，预测神经周围或血管侵犯的CT表现的敏感性为88%；特异性为83%；阳性预测值为85%；阴性预测值为84%。
CT表现可用于预测口腔肿瘤的神经周围或血管侵犯。
