Yamazaki H, Oi H, Matsushita M, Inoue T, Tang J T, Inoue T
Department of Radiation Oncology, Osaka University Medical School, Japan.
Radiat Med. 1995 Jul-Aug;13(4):163-5.
Serum C-reactive protein (sCRP) levels were measured before and after angiography and transcatheter arterial embolization (TAE) in 25 patients (four angiography, 21 TAE for hepatocellular carcinoma) to examine the correlation of sCRP to patients' reaction to TAE and the efficacy of TAE. Four patients without TAE showed little elevation of sCRP. Twenty-one patients with TAE showed a significant increase in sCRP. Peak levels of sCRP in the patients who achieved partial response were higher than those of the no-change group after TAE (p = 0.005). Peak sCRP levels of patients who showed an adverse reaction to TAE were higher than those of patients with no adverse reaction (p = 0.02). Increased sCRP after TAE reflects not only the degree of untoward reaction but also the effectiveness of TAE. Therefore, measurement of sCRP may be a useful means to assess the effect of TAE.
对25例患者（4例行血管造影术，21例行经导管动脉栓塞术（TAE）治疗肝细胞癌）在血管造影术和TAE前后测量血清C反应蛋白（sCRP）水平，以研究sCRP与患者对TAE的反应及TAE疗效之间的相关性。4例未接受TAE的患者sCRP升高不明显。21例接受TAE的患者sCRP显著升高。部分缓解患者的sCRP峰值水平高于TAE后无变化组（p = 0.005）。对TAE有不良反应患者的sCRP峰值水平高于无不良反应患者（p = 0.02）。TAE后sCRP升高不仅反映了不良反应的程度，还反映了TAE的有效性。因此，测量sCRP可能是评估TAE效果的有用方法。
