Kadas I, Vagvolgyianna M
Morphol Igazsagugyi Orv Sz. 1977 Feb;17(1):64-70.
Occurrence of the hepatitis B surface antigen in the paraffin-embedded sections of needle-hepatic-biopsy taken for diagnostic purpose from 138 patients (108 adults and 30 children) and from 52 simptomless hepatitis B antigen positive donors was investigated (modified orcein dye, "ground glass" hepatocytes). The following was established: I. this technique is simple, reliable and useful; 2. antigen can be detected first of all in hepatocytes of simptomless carriers; 3. it seems, that the antigen-positivity in tissue is in inverse ratio to the activity of hepatic lesion; 4. in the material taken from the children ground-glass hepatoyctes could not be revealed. Only in one case could be revealed a minimal orcein-positivity. 5. By technical reasons in needle-biopsy material a false-negative result can not be regarded as a rarity.
对138例患者（108名成人和30名儿童）以及52名无症状乙肝抗原阳性供血者为诊断目的所取的针吸肝活检石蜡包埋切片中乙肝表面抗原的出现情况进行了研究（改良orcein染料，“毛玻璃样”肝细胞）。得出以下结论：1. 该技术简单、可靠且有用；2. 首先可在无症状携带者的肝细胞中检测到抗原；3. 组织中的抗原阳性似乎与肝脏病变的活动呈反比；4. 在取自儿童的材料中未发现毛玻璃样肝细胞。仅在1例中发现了极轻微的orcein阳性。5. 由于技术原因，针吸活检材料中的假阴性结果并非罕见。
