迈向人体生理组学建模。
Toward modeling the human physionome.
作者信息
Bassingthwaighte J B
机构信息
Center for Bioengineering, University of Washington, Seattle 98195, USA.
出版信息
Adv Exp Med Biol. 1995;382:331-9. doi: 10.1007/978-1-4615-1893-8_32.
The physionome is the description of the physiological dynamics of the normal intact organism. The march of science brings us now into the era where integration of the various facets of the knowledge of biology and medicine has become a major issue. Modeling is a vehicle for the combining of information from molecular biology, biophysics, and medical biology, but must be combined with strategies for databasing the raw data with greater efficiency than is currently possible. The lessons from the genome project can be applied to the next level major projects, the morphonome and the physionome, the objective being to put integrated forms of the data into the hands of physicians and medical scientists.
生理组是对正常完整生物体生理动态的描述。科学的发展使我们进入了一个时代，生物学和医学知识各个方面的整合已成为一个主要问题。建模是整合分子生物学、生物物理学和医学生物学信息的一种手段，但必须与能以比目前更高的效率对原始数据进行数据库化处理的策略相结合。基因组计划的经验教训可应用于下一级重大项目，即形态组和生理组，目标是将整合后的数据形式交到医生和医学科学家手中。
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