目前，在胃癌的根治性手术治疗中应常规进行扩大淋巴结清扫术（D2切除术）。
Extended lymph node dissection (D2 resection) should now be performed routinely in the curative surgical treatment of gastric carcinoma.
作者信息
Ravichandran D, Lamah M, Carty N J, Johnson C D
机构信息
University Surgical Unit, Southampton University Hospitals.
出版信息
Ann R Coll Surg Engl. 1995 Nov;77(6):431-6.
Abstract
Gastric cancer has a dismal prognosis in the Western world. In contrast, in Japan where extended lymphadenectomy is the rule in curative gastric cancer surgery, the prognosis is much better. The arguments for and against the adoption of this procedure in the West are presented. This procedure is safe in the hands of experienced surgeons and by improving locoregional control, may improve survival. However, in the absence of controlled data supporting a survival advantage, the excess morbidity and mortality of this extended procedure in the West may not be justified.
摘要
在西方世界，胃癌的预后很差。相比之下，在日本，扩大淋巴结清扫术是根治性胃癌手术的常规操作，其预后要好得多。文中阐述了在西方支持和反对采用该手术方法的观点。在经验丰富的外科医生手中，此手术是安全的，并且通过改善局部区域控制，可能提高生存率。然而，在缺乏支持生存优势的对照数据的情况下，西方这种扩大手术带来的额外发病率和死亡率可能并不合理。
相似文献
1
Extended lymph node dissection (D2 resection) should now be performed routinely in the curative surgical treatment of gastric carcinoma.目前，在胃癌的根治性手术治疗中应常规进行扩大淋巴结清扫术（D2切除术）。
Ann R Coll Surg Engl. 1995 Nov;77(6):431-6.
2
Does extended lymphadenectomy influence prognosis of gastric carcinoma after curative resection?扩大淋巴结清扫术对胃癌根治性切除术后的预后有影响吗？
Hepatogastroenterology. 2000 Sep-Oct;47(35):1470-4.
3
Resection for gastric cancer in the community.社区胃癌切除术
Semin Oncol. 2005 Dec;32(6 Suppl 9):S90-3. doi: 10.1053/j.seminoncol.2005.06.010.
4
Extended lymphadenectomy in gastric cancer: when, for whom and why.胃癌扩大淋巴结清扫术：时机、对象及原因
Ann R Coll Surg Engl. 1998 Jan;80(1):16-24.
5
Current status and future perspectives in gastric cancer management.胃癌治疗的现状与未来展望
Cancer Treat Rev. 2000 Aug;26(4):243-55. doi: 10.1053/ctrv.2000.0164.
6
[Lymph node excision in cancer of the stomach].[胃癌的淋巴结切除术]
J Chir (Paris). 1998 Oct;135(4):155-61.
7
[The role of superextended lymphadenectomy (D4) in gastric cancer].[扩大根治性淋巴结清扫术（D4）在胃癌中的作用]
Minerva Chir. 2004 Aug;59(4):325-35.
8
Extended lymph-node dissection for gastric cancer: a challenge for better survival results.
Neth J Surg. 1990 Feb;42(1):3-8.
9
The effectiveness of extended lymph node dissection for gastric cancer performed in Costa Rica under the supervision of a Japanese surgeon: a comparison with surgical results in Japan.在日本外科医生监督下于哥斯达黎加开展的胃癌扩大淋巴结清扫术的有效性：与日本手术结果的比较。
Am J Surg. 2008 Jan;195(1):53-60. doi: 10.1016/j.amjsurg.2007.01.028.
10
Evidence of survival benefit of extended (D2) lymphadenectomy in western patients with gastric cancer based on a new concept: a prospective long-term follow-up study.基于新概念的西方胃癌患者扩大（D2）淋巴结清扫术生存获益的证据：一项前瞻性长期随访研究。
Surgery. 1998 May;123(5):573-8. doi: 10.1067/msy.1998.88094.
引用本文的文献
1
Antibiotic Bowel Decontamination in Gastrointestinal Surgery-A Single-Center 20 Years' Experience.胃肠道手术中的抗生素肠道去污——单中心20年经验
Front Surg. 2022 May 16;9:874223. doi: 10.3389/fsurg.2022.874223. eCollection 2022.
本文引用的文献
1
Comparison of the prognostic significance between the number of metastatic lymph nodes and nodal stage based on their location in patients with gastric cancer.基于胃癌患者转移淋巴结数量及其位置的淋巴结分期之间预后意义的比较。
J Clin Oncol. 1993 Oct;11(10):1894-900. doi: 10.1200/JCO.1993.11.10.1894.
2
Extensive versus limited lymph node dissection for gastric cancer: a comparative study of 320 patients.胃癌广泛与有限淋巴结清扫术：320例患者的对比研究
Br J Surg. 1993 Sep;80(9):1153-6. doi: 10.1002/bjs.1800800930.
3
Prognostic relevance of systematic lymph node dissection in gastric carcinoma. German Gastric Carcinoma Study Group.胃癌系统性淋巴结清扫的预后相关性。德国胃癌研究组
Br J Surg. 1993 Aug;80(8):1015-8. doi: 10.1002/bjs.1800800829.
4
Gastric cancer: a curable disease in Britain.胃癌：在英国可治愈的疾病。
BMJ. 1993 Sep 4;307(6904):591-6. doi: 10.1136/bmj.307.6904.591.
5
Prognostic value of the number of metastatic lymph nodes in gastric cancer with radical surgery.根治性手术后胃癌转移淋巴结数量的预后价值
J Surg Oncol. 1993 Aug;53(4):247-51. doi: 10.1002/jso.2930530412.
6
Adjuvant therapy after curative resection for gastric cancer: meta-analysis of randomized trials.胃癌根治性切除术后的辅助治疗：随机试验的荟萃分析
J Clin Oncol. 1993 Aug;11(8):1441-7. doi: 10.1200/JCO.1993.11.8.1441.
7
A prospective randomized trial comparing R1 subtotal gastrectomy with R3 total gastrectomy for antral cancer.一项比较R1次全胃切除术与R3全胃切除术治疗胃窦癌的前瞻性随机试验。
Ann Surg. 1994 Aug;220(2):176-82. doi: 10.1097/00000658-199408000-00009.
8
Cancer prevention: setting the scene.癌症预防：开篇介绍
BMJ. 1994 May 28;308(6941):1415-20. doi: 10.1136/bmj.308.6941.1415.
9
Results of total gastrectomy for gastric cancer.胃癌全胃切除术的结果。
Am J Surg. 1980 Nov;140(5):636-8. doi: 10.1016/0002-9610(80)90046-x.
10
Prognostic significance of combined splenectomy or pancreaticosplenectomy in total and proximal gastrectomy for gastric cancer.
Am J Surg. 1981 Nov;142(5):546-50. doi: 10.1016/0002-9610(81)90422-0.
Zotero 插件