Boyle C A, Dobson A J
Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, NSW, Australia.
Aust N Z J Med. 1995 Aug;25(4):316-23. doi: 10.1111/j.1445-5994.1995.tb01896.x.
In Australia information on the incidence of acute myocardial infarction (AMI) is available from routinely collected morbidity and mortality data. Given that these data are used for monitoring AMI it is important to assess their quality.
This paper examines the accuracy of the hospital records and death certificates.
Morbidity and mortality data were compared with the Newcastle heart disease register which is part of the WHO MONICA Project for 1986-1991 and sensitivity and positive predictive values calculated.
For non-fatal AMI the hospital diagnostic coding had sensitivity of 78.9% (95% confidence interval [CI] 77.1%-80.7%), and positive predictive value of 65.6% (95% CI 63.7%-67.4%). Sensitivity was higher for men than for women and decreased with increasing age. Sensitivity was higher in those with no history of either AMI or other ischaemic heart disease (IHD), higher in current smokers than ex-smokers or never smokers, and lower in those with a self-reported history of high blood pressure. Sensitivity also varied among hospitals. Positive predictive value varied only with hospital. Both sensitivity and positive predictive value were high for death certificate data--89.9% (95% CI 88.4%-91.3%) and 96.0% (95% CI 95.1%-97.0%), respectively.
Although the mortality data appear to be quite accurate, the hospital data alone are not accurate enough to be used to estimate rates or trends of heart attacks. Additional data are required in order to determine numbers of non-fatal AMIs accurately.
在澳大利亚,可从常规收集的发病率和死亡率数据中获取急性心肌梗死(AMI)的发病信息。鉴于这些数据用于监测AMI,评估其质量很重要。
本文研究医院记录和死亡证明的准确性。
将发病率和死亡率数据与纽卡斯尔心脏病登记册进行比较,该登记册是世界卫生组织MONICA项目1986 - 1991年的一部分,并计算敏感性和阳性预测值。
对于非致命性AMI,医院诊断编码的敏感性为78.9%(95%置信区间[CI]77.1% - 80.7%),阳性预测值为65.6%(95%CI 63.7% - 67.4%)。男性的敏感性高于女性,且随年龄增长而降低。在无AMI或其他缺血性心脏病(IHD)病史的人群中敏感性较高,当前吸烟者的敏感性高于既往吸烟者或从不吸烟者,而有自我报告高血压病史的人群中敏感性较低。敏感性在不同医院之间也有所差异。阳性预测值仅因医院而异。死亡证明数据的敏感性和阳性预测值都很高,分别为89.9%(95%CI 88.4% - 91.3%)和96.0%(95%CI 95.1% - 97.0%)。
尽管死亡率数据似乎相当准确,但仅医院数据不足以准确用于估计心脏病发作的发生率或趋势。需要额外的数据以准确确定非致命性AMI的数量。