Dunston-Boone G, Kuhlman K, Kaufmann M
Department of Obstetrics and Gynecology, Jefferson Medical College, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Am J Perinatol. 1995 Sep;12(5):342-6. doi: 10.1055/s-2007-994492.
This was a retrospective study of acoustic stimulation response and perinatal outcome of 688 fetuses undergoing nonstress testing. Acoustic stimulation was performed within 7 days of delivery, and responses were classified based on the presence of an acceleration, deceleration, or both. Responses were correlated with perinatal outcome. Abnormal outcome was defined as: cesarean section for nonreassuring fetal heart rate patterns with an acidotic umbilical artery cord gas; delivery at less than 32 weeks for nonreassuring antenatal fetal testing; meconium aspiration syndrome or mechanical ventilation at 36 weeks or greater; neonatal seizures; 5-minute Apgar score less than 7; and stillbirth. Fetuses who demonstrated deceleration responses were significantly more likely to have abnormal perinatal outcomes when compared with those with acceleration responses (p < 0.001). Although combination acceleration-deceleration responses were more often associated with abnormal perinatal outcome when compared with pure acceleration responses, differences were not significant. A deceleration response following acoustic stimulation is associated with increased risk for adverse perinatal outcome and may merit further evaluation.
这是一项对688例接受无应激试验的胎儿的声刺激反应及围产期结局的回顾性研究。在分娩前7天内进行声刺激,并根据是否存在加速、减速或两者皆有对反应进行分类。将反应与围产期结局进行关联分析。异常结局定义为:因胎儿心率模式不令人安心且脐动脉血气呈酸中毒而行剖宫产;因产前胎儿检测不令人安心而在32周前分娩;在36周及以上发生胎粪吸入综合征或机械通气;新生儿惊厥;5分钟阿氏评分低于7分;以及死产。与有加速反应的胎儿相比,表现出减速反应的胎儿出现异常围产期结局的可能性显著更高(p<0.001)。尽管与单纯加速反应相比,加速 - 减速联合反应更常与异常围产期结局相关,但差异不显著。声刺激后的减速反应与不良围产期结局风险增加相关,可能值得进一步评估。